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Some people report noticing improvements in recovery, comfort, or mobility within a few weeks, while others may require a longer period before experiencing noticeable benefits

Chronic neural inflammation and central nervous system (CNS) injury can also increase blood brain barrier permeability, allowing immune cells such as macrophages to migrate into the CNS from the bloodstream (Minogue, 2017)

10.1016/j.cca.2017.04.006 [DOI] [PubMed] [Google Scholar] 74.Peng YF, Zhang L, Pan GG, Wei YS

The 60-day washout recommendation leaves a gray zone between 30 and 60 days where serum clearance is likely complete but tissue depot effects remain theoretically possible